Better than Hydroxychloroquine? Two New Studies Show Quercetin Improves COVID Outcomes Robert Gorter, MD, PhDRobert Gorter, MD, PhD

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Two studies suggest that this antiviral, anticoagulant, and anti-inflammatory agent is an alternative to hydroxychloroquine. In addition, it is much less expensive, easier to obtain, and COVID clears up faster than those given painkillers and antibiotics. Where are the media?.

Two recently published studies confirm that quercetin is useful as adjunctive therapy in the early outpatient treatment of mild SARS-CoV-2 infection

In one study, the virus cleared more quickly in SARS-CoV-2 patients who received quercetin in addition to analgesics and an antibiotic than those who received only painkillers and antibiotics, and a greater number of patients reported a reduction in symptoms.

In the second study, the daily addition of quercetin for one month reduced the frequency and length of hospitalization, the need for non-invasive oxygen therapy, intensive care, and death rates.

Quercetin has antiviral, anticoagulant, anti-inflammatory, and antioxidant properties, all of which are important in the treatment of SARS-CoV-2 infection.

Quercetin also inhibits the binding of specific spike proteins to your ACE2 receptors, blocking the virus from its ability to infect your cells. It has also been shown to directly neutralize viral proteins critical for SARS-CoV-2 replication.

In a newsletter dated August 21, 2021, 1, Dr. Michael Murray’s use of quercetin for the symptoms of respiratory infections. In November 2020, he had had a “very mild and brief bout of COVID-19” and one of his “secret weapons,” he believes, may have been quercetin.

He also tells of an anecdotal story of a friend who developed suspicious respiratory symptoms. His friend had taken some supplements that were said to provide protection, but still wasn’t feeling well.

As it turned out, the only thing he hadn’t taken was quercetin, and as soon as he did, that same day, his symptoms began to subside. This experience, Murray says, “concurs with the results of two clinical studies” recently published.

Quercetin appears to be a very safe, much cheaper, and more readily available alternative to hydroxychloroquine, and it works through a similar mechanism, driving zinc into the cells to stop viral replication.

Statistical Improvement of Clinical Outcomes

In the first study, 2 were 42 COVID-19 outpatients divided into two groups. One group of 21 patients received standard medical therapy consisting of analgesics and an antibiotic (acetaminophen 500-milligram (mg) to 1000-mg dose if body temperature was above 37.5 degrees C – 99.5 F – with a maximum daily dose of 3 grams, and 500 mg of azithromycin for three consecutive days).

The other group of 21 patients received standard therapy plus the equivalent of 600 mg quercetin per day (divided into three doses) for seven days, followed by a further seven-day course of 400 mg quercetin per day (divided into two doses).

The quercetin used was a brand name formulated with sunflower lecithin, which has been shown to increase absorption in the gut by up to 20 times, compared to pure quercetin formulations.

The main results evaluated were virus removal and symptoms. After one week of treatment, 16 of the 21 patients in the quercetin group tested negative for SARS-CoV-2, and 12 reported that all symptoms had subsided.

In the standard group, only two tests were negative and four had partially improved symptoms. At the end of week 2, the five remaining patients in the quercetin group had tested negative. In the standard care group, 17 of the 19 remaining patients had a negative test result and one of them had died.

As noted by the authors, “quercetin supplementation statistically shortens the timing of molecular test conversion from positive to negative, simultaneously reducing symptom severity and negative predictors of COVID-19.”

“These results are impressive and hopefully additional studies will be conducted on hospitalized patients to see how quercetin could be helpful in more severe cases,” Murray wrote in his newsletter.

Quercetin reduces hospitalizations and deaths

The second study 3 – a prospective, randomized, controlled, and open-label study – gave 152 COVID-19 outpatients a daily dose of 1,000 mg quercetin for 30 days to evaluate its adjuvant effects in the treatment of early symptoms and prevention of serious infections. According to the authors:

“The results revealed a reduction in frequency and length of hospitalization, in need for non-invasive oxygen therapy, in progression to intensive care units, and in death rates. The results also confirmed the very high safety profile of quercetin and suggested possible anti-fatigue and appetite-promoting properties.

QP (Quercetin Phytosome®) is a safe agent and, when used in the early stages of a viral infection with standard care, may help improve early symptoms and prevent the severity of COVID-19 disease. It is suggested that a double-blind, placebo-controlled study be conducted urgently to confirm the results of our study.”

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Mechanisms of Action…

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