…a Serious Adverse Safety Signal of Myocarditis, Particularly in Children and Young Adults Resulting in Hospitalization and Death’
“The strong signal of a five times higher risk of myocarditis in 15-year-olds following dose 2 is indicative of a dose–response relationship. If the effects of each dose were the same, then we would expect to see the same number of reports filed following each dose. This indicates that the effects of dosing a second time may be more damaging and cumulative with each additional dose. In such cases, it is possible that myocarditis was subclinical after dose 1 and became symptomatic after dose 2.
The clinical implications of acute myocarditis in younger individuals as a result of uncontrolled production of the SARS-CoV-2 spike protein within cardiac myocytes and cardiac support cells are unknown. If myocarditis has developed after the first injection, then subsequent administrations should be avoided at all costs. Sustained elevations of cardiac troponin, reduction in left and right ventricular function, large areas of inflammation or scar on imaging, and cardiac arrhythmias all portend a poor prognosis for the development of heart failure and cardiac death.”
Read the full story here: https://journals.sagepub.com/doi/10.1177/20420986241226566#